Answer to Question #149617 in Biochemistry for nayaa

Question

Describe the mechanisms by which enzymes lower activation energy

Answer 1

Enzymes lower activation energy through various means, including positioning substrates together in the proper orientation, applying torque on the substrates, providing the proper charge or pH microenvironment, and adding or removing functional groups on the substrates. In each of these methods, the enzyme functions to stabilize the transition state between the substrates as they are transformed into products.