Answer to Question #285658 in Biochemistry for saeyipark

Question

Explain how ATP was produced in penthose phosphate pathway.

Answer 1

The definitive enzyme of the pathway is 6-phosphogluconate dehydrogenase. Subsequent cleavage of the pentose phosphate typically produces glyceraldehyde 3-phosphate and acetate or acetyl phosphate (depending on the enzyme system). The net yield of ATP for this pathway is typically only 1 ATP per glucose molecule.