Answer to Question #197778 in Cell Biology for Noah

Question

Complete the blank

1-The extrinsic pathway in apoptosis is mediated by , while the intrinsic pathway is mediated by injury.

2- Caspases is a family of intracellular proteases dependent on              (which amino acid) that play a pivotal role in the apoptosis.

Answer 1

The extrinsic pathway in apoptosis is mediated by the death receptor, while the intrinsic pathway is mediated by cell injury.

Caspases is a family of intracellular proteases dependent on caspase activation leading to substrate cleavage and, ultimately, cell death.