Answer to Question #239681 in Cell Biology for PJ Saints

Question

if a drug partly blocked a membrane potassium channels, how does it affect the action potential? free answers

Answer 1

These drugs bind to and block the potassium channels that are responsible for phase 3 repolarization. Therefore, blocking these channels slows (delays) repolarization, which leads to an increase in action potential duration and an increase in the effective refractory period (ERP).