Answer to Question #335655 in Cell Biology for ggg123

Question

How would high levels of ACTH affect secretions of cortisol from the adrenal glands? How would high levels of cortisol affect ACTH?

Answer 1

High levels of ACTH lead to hypersecretion of cortisol and induce stress response, but in order to maintain homeostasis the negative feedback loop comes into being and excessive amounts of cortisol suppress production of ACTH.