Answer to Question #182366 in Genetics for Sam

Question

during protein synthes Can you say in which stages do these errors take place.

Also what impact do they have on the end products of protein synthesis

Answer 1

Errors takes place during translation elongation, which lead to incorporation of an incorrect amino acid, frameshifting, readthrough of stop codons, or premature termination, which may produce proteins which deviate from encoded amino acid sequence. Errors in the protein synthesis usually disrupt cellular fitness, result to disease phenotypes, and shape gene as well as genome evolution.