Answer to Question #265759 in Genetics for Kelly

Question

The following RNA sequence is a pre-mRNA which has just been transcribed and has not undergone processing yet. It contains a start codon, a stop codon and one intron. Identify the location of the intron and write the mature mRNA transcript. Use a codon table to translate the protein encoded by this mRNA. After determining the protein sequence, use the sequence to show an example of each type of mutation listed and how it would affect the protein.

5’UACGGAUGUCGUUCCACGGAACAGUACUUGACGCCAGCCCCUGGUAUAGUCAGUG 3’

missense?

nonsense?

frameshift?

Answer 1

Upstream of individual genes, sequences of DNA called promoters determine when proteins are produced and in what amounts.