In November 2024
Answer to Question #338690 in Genetics for acey
Why can't normal hydrogen bonding with nitrogenous bases of DNA occur when the molecule is in duplex/helix form?
If the DNA molecule is in a helical form, then not only the spatial arrangement of atoms in complementary nucleotides between which a hydrogen bond is established changes, but the distance between these atoms also changes, which makes the formation of hydrogen bonds impossible.
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#339914 on Dec 2023
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