Answer to Question #154473 in Microbiology for Neha

Question

1.    What kind of mouse model will you use in these studies? Briefly explain.

a. You want to study the innate immune response against a pathogen.

b. You want to study the adaptive immune response against a pathogen

Answer 1

a) The innate response is characterized by being the first line of defense that occurs rapidly in which leukocytes such as neutrophils, monocytes, macrophages, eosinophils, mast cells, dendritic cells, etc., are involved.

b) Adaptive immune responses is to destroy invading pathogens and any toxic molecules they produce. Because these responses are destructive, it is crucial that they be made only in response to molecules that are foreign to the host and not to the molecules of the host itself.