Answer to Question #309428 in Cell Biology for justine siamunyano

Question

Research has shown that alcohol inhibits the release of antidiuretic hormone from the posterior lobe of pituitary gland. suggest what effects this has on the body and how it might contribute to unpleasant "morning after" feeling commonly described as "hangover".

Answer 1

Diagnosis alcohol inhibits the release of antidiuretic hormone from the posterior lobe of pituitary gland. suggest what effects this has on the body and how it might contribute to unpleasant "morning after" feeling commonly  Diagnosis is confirmed by clinical, laboratory and radiographic findings: ▪ plasma GH – raised ▪ oral glucose tolerance test – fails to suppress GH ▪ serum insulin-like growth factor 1 – raised ▪ CT and MRI.

Treatment ▪ Neurosurgery and/or radiation ▪ Dopamine agonists (bromocriptine) and somatostatin analogues (sandostatin).

Prognosis Acromegalic patients have a decreased life expectancy, because of cardiovascular diseases, tumours and endocrine problems. Cardiac failure is the major cause of death.

Oral findings ▪ The skull is thickened and the paranasal air sinuses are enlarged ▪ Mandibular enlargement leads to class III malocclusion with spacing of the teeth and thickening of all soft tissues, but most conspicuously of the face ▪ Enlargement of the dental bases leads to relatively sudden ill-fitting dentures ▪ Macroglossia and thick lips are due to soft tissue growth ▪ Apical hypercementosis ▪ Sialosis ▪ Hyperpigmentation of the naso-labial fold ▪ Progressive periodontal disease has been described – probably related to dental malposition and tissue enlargement