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A teenage boy asks his parents “Why do I look similar but slightly different from


my brother?” Using language a layperson would understand, how would you


explain to him about the key events that take place to create this genetic


variation? During what process do these occur and how do they happen? Write 500 words at least.

A teenage boy asks his parents “Why do I look similar but slightly different from my brother?” Using language a layperson would understand, how would you explain to him about the key events that take place to create this genetic variation? During what process do these occur and how do they happen?


In a 39-year-old woman, the 5th pregnancy, which occurred with gestosis and the threat of



termination, ended in labor at 36 weeks. The newbom girl, with a body weight of 2700 g and a body



length of 48 cm, screamed immediately. On examination, there is swelling of the hands and feet, a short



Ticket Ni3



neck with excessive skin folds, and General muscle hypotension.



Questions: 1. Your diagnosis. Write the karyotype



2. Determine the type of mutation. Describe the mechanism of occurrence of this disease



3. What are the methods of diagnosis of this group of diseases?


evaluate the significant of chromosomal behaviour during cell division and how it leads to variation provide justified arguments as to how crossing over and independent assortment leading to the variation within an organism


discuss the behaviour of the chromosomes during mitosis and meiosis in each stage of cell division

ensure to cover - mitosis - interphase, prophase, metaphase, anaphase, telophase

meiosis - interphase prophase I, metaphase I, anaphase I, telophase I, cytokinesis, prophase II, metaphase II, anaphase II, telophase II, cytokinesis


When a dark blue fish and a light blue fish with dark blue fins were mated , all offspring became dark blue. What could also be seen was that part of the offspring got light gray fins.



Explain with the help of genetics why all fish turn dark blue.



Use relevant terms in your explanation and also show using intersection diagrams.

Now we look at the fins instead. How come some of the offspring get gray fins instead of dark blue like the parents?





When a dark blue fish and a light blue fish with dark blue fins were mated , all offspring became dark blue. What could also be seen was that part of the offspring got light gray fins.



If a sample of DNA is 75 base pairs long, how many amino acids will be present in the polypeptide chain that is fomed?


Following tetrads are observed in yeast crosses involving three pairs of  heterozygous genetic markers (A/a; B/b) (C/c; D/d) (E/e; F/f): 

Cross I (A/a; B/b) Cross II (C/c; D/d) Cross III (E/e; F/f) AB Ab CD CD EF Ef EF AB Ab CD Cd EF Ef Ef ab aB cd cD ef eF eF ab aB cd cd ef eF ef 

---- ----- ------ ----- ---- ----- ----  95 90 50 20 80 5 20  


What is the genetic map distance (in cM or M) between the two pairs of loci in each of the  three crosses?




Albinism, the total lack of pigment, is due to a recessive gene. A man and woman plan to marry and wish to know the probability of their having any albino children. What are the probabilities if: 

1.     both are normally pigmented, but each has one albino parent. 

2.     the man is an albino, the girl is normal, but her father is an albino. 

3.     the man is an albino and the girl's family includes no albinos for at least three generations.


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