Answer to Question #199604 in Bioinformatics for Ayesha Arshad

Question

What are different nucleotide and protein databases? Describe the salient features of each with emphasis on pros and cons. 

Answer 1

Different nucleotide are; adenine (A), thymine (T), guanine (G), and cytosine (C). These nucleotide have three features: (1) a nitrogenous base, (2) a pentose, and (3) a phosphate.

A protein database is one or more datasets about proteins, which could include a protein's amino acid sequence, conformation, structure, and features such as active sites.

Protein databases are categorized into:

• Sequence databases: GenBank, European Nucleotide Archive and DNA Data Bank of Japan.
• Secondary databases: UniProt, database of protein sequences grouping together Swiss-Prot, TrEMBL and Protein Information Resource.
• Other databases: Protein Data Bank, Ensembl and InterPro.